Senior Research Associate – Downstream Process Development (Protein Purification, AKTA, UF/DF, ADC)

Immediate need for a talented Senior Research Associate – Downstream Process Development (Protein Purification, AKTA, UF/DF, ADC). This is a 06+ months contract opportunity with long-term potential and is located in Oceanside, CA(Onsite). Please review the job description below and contact me ASAP if you are interested.

Job ID: 26-13764

Pay Range: $35 - $39.50/hour.  Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).

Key Responsibilities:

• Design and execute experiments supporting downstream process development (DSP)
• Perform protein purification using:
• AKTA chromatography systems
• Tangential Flow Filtration (TFF) / UF/DF
• Harvest centrifugation and filtration
• Apply Design of Experiments (DOE) for process optimization
• Support scale-up activities from bench to pilot and manufacturing scale
• Develop scale-down models and assess process robustness
• Analyze and interpret data; identify trends and process improvements
• Collaborate with cross-functional teams (MSAT, Manufacturing, Analytical, QA)
• Support technology transfer to GMP manufacturing
•  Assist in process characterization, validation, and documentation
• Present findings and contribute to team discussions

Key Requirements and Technology Experience: 

• BS degree + 2+ years of relevant experience OR MS degree + 0+ years of relevant experience
• Degree in Biochemistry, Chemical/Biochemical Engineering, Chemistry, or related field
• Hands-on experience in downstream process development (NOT upstream)
• Strong experience with:
• AKTA chromatography systems
• UF/DF or Tangential Flow Filtration (TFF)
• Chromatography (Protein A, IEX, HIC preferred)
• Experience with:
• Process scale-up (bench → pilot → manufacturing)
• Scale-down models and process robustness
• Design of Experiments (DOE)
• Experience with Antibody Drug Conjugates (ADC)
• Knowledge of cGMP and technology transfer
• Experience in biologics (mAbs, bispecifics, fusion proteins)
• Familiarity with analytical methods (SEC/HPLC, CE, HCP)

Our client is a leading Healthcare Industry and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration.

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