Research Associate II

Immediate need for a talented Research Associate II. This is a 12+months contract opportunity with long-term potential and is located in Waltham, MA (Onsite). Please review the job description below and contact me ASAP if you are interested.

Job ID:26-14221

Pay Range: $40 - $51/hour.  Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).

Key Responsibilities:

• HM Notes:
• Slight flex on work hours Open to candidates willing to relocate at their own expense No extensions at this time Free parking onsite
• Estimated once a week, position may work more than 8 hours per day; however, limited to 40 hours per week.
• Typically, advance notice of OT will be provided 3-4 days in advance.
• Lab Based position, primary 70-80%, No exposure to extreme heat or long duration in cold rooms .
• Interview process: 1 st round, interview manager (zoom) 2nd round, onsite panel interview (unless nonlocal candidate)
• Support to develop, design and conduct viral vector purification experiments and evaluate new technologies to increase product yield and process understanding
• Develop, maintain and demonstrate advanced knowledge of principals and techniques in column chromatography and other areas of downstream purification
• Maintain industry knowledge and awareness of new and relevant technologies, and be willing to publish findings and to speak both internally and externally as industry leaders
• Lead / support development of study design, optimization of purification process conditions, media screening and perform troubleshooting experiments and communicate findings with appropriate working groups
• Perform data analyses, contribute to technical reports and internal/external presentations
• Support scale-up activities to implement a manufacturing process based on applied DSP knowledge
• Communicate effectively with internal and external teams, e.g. CDMOs for tech transfer activities
• Contribute to manuscript and patent writing for external publications and patent applications, respectively
• Self-motivated and display sound technical judgement
• Build a culture of support and collaboration among colleagues

Key Requirements and Technology Experience:

• Key Skills; AAV, non-viral purification development, AKTA .
• Purification experience/ Protein purification chromatography
• Critical thinking
• Strong communication
• Professional industry experience is required for bachelor's and master's degree level candidates.
• AKTA must have
• Filtra ration
• Must have protein purification
• AV experience, to have
• Bachelor’s degree with a minimum of 2 years min of relevant experience
• Master’s degree with a minimum of 0+ years, will only consider in school experience only for MS Candidates
• No PHD candidates, overqualified.
• DOE/ Design of Experiments a plus
• BSL Biosafety Lab Level II experience a plus
• Master’s degree in biological sciences or related discipline, or Bachelor’s degree with a minimum of 2 years of relevant experience
• Experience, knowledge and understanding of purification technologies and operations such as:
• Depth filtration
• AKTA or automated protein purification chromatography
• Tangential flow filtration or UF/DF
• Virus clearance and inactivation
• Filtration unit operations at various scales
• Strong grasp of chromatography principles and modalities
• Experience with process technology transfers and performing gap analyses and risk assessments
• Expertise in technical report writing
• Ability to learn and perform viral vector analyses using new tools and techniques
• Exhibits good laboratory practices including writing neat laboratory procedures in lab notebooks.
• Familiarity with purification of viral vectors
• Knowledge of basic analytical tools such as spectrophotometry, ELISA, HPLC, and SDS-PAGE
• Basic understanding of the principles of Quality by Design and ability to apply DOE to downstream development
• Understanding of viral clearance study design and execution strategy preferred
• Experience with large-scale unit operations
• Ability to work in Biosafety Level 2, follow safe lab procedures and maintain good laboratory practices (GLPs)
• Ability to work under minimal supervision and function within a collaborative, team-oriented environment
• Excellent organization and communication skills
• Ability to build and nurture cross-functional relationships
• Ability to communicate and represent group in diverse, multi-functional meetings
• Ability to stand and work with lab bench equipment in laboratory

Our client is a leading Pharmaceutical Industry, and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration.

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