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Scientist II - Structural Biologist

Pyramid Consulting, Inc Waltham, MA (Onsite) Contractor

Immediate need for a talented Scientist II - Structural Biologist . This is a 12+months contract opportunity with long-term potential and is located in Waltham, MA (Onsite). Please review the job description below and contact me ASAP if you are interested.

Job ID: 25-76964

Pay Range: $65 - $68/hour.  Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).

Key Responsibilities:

  • Design and execute structural biology experiments to characterize AAV capsid proteins
  • Utilize cryo-EM and other biophysical techniques to determine AAV capsid structures
  • Analyze structure-function relationships to guide rational design of novel AAV vectors
  • Collaborate with gene therapy and protein engineering teams to develop improved AAV vectors
  • Present findings to internal teams and at scientific conferences
  • Publish research in peer-reviewed journals

Key Requirements and Technology Experience: 

  • Key Skills; AAV Capsid, structural biology, cryo-EM, X-ray crystallography, Protein Engineering
  • PhD (or equivalent) in Structural Biology, Biophysics, or closely related field; no post-doctoral experience necessary
  • Necessary expertise in cryo-EM, X-ray crystallography, or related structural biology techniques
  • Preferred (but not essential) experience with structural characterization of viral capsids, preferably AAV
  • Strong background in protein biochemistry and molecular biology
  • Experience with structure-based protein engineering is highly desirable
  • Excellent analytical, problem-solving, and communication skills
  • Candidates must be authorized to work in the United States
  • Experience with computational modeling of protein structures
  • Knowledge of gene therapy applications and vector development
  • Familiarity with high-throughput screening approaches
  • Track record of publications in structural biology or related fields

Our client is a leading healthcare Industry and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration.

Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

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Job Snapshot

Employee Type

Contractor

Location

Waltham, MA (Onsite)

Job Type

Other

Experience

Not Specified

Date Posted

07/02/2025

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